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The decrease in iron concentration immediately after the 100-km ultra-marathon was smaller in the VD group than CON (p less then 0.05). These data show that various vitamin D3 status can affect the post-exercise metabolism of serum iron.Neurodegenerative diseases represent a significant unmet medical need in our aging society. There are no effective treatments for most of these diseases, and we know comparatively little regarding pathogenic mechanisms. Among the challenges faced by those involved in developing therapeutic drugs for neu