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Immunoblot, immunofluorescence, and immunohistochemistry analyses were implemented. A subcutaneous tumor model was developed to investigate the role of LRG1. . Urine samples from patients with epithelial ovarian cancer (EOC) exhibited a unique expression of exosomal LRG1, and elevated levels of LRG1 correlated strongly with a less favorable outcome. Functional studies demonstrated a relationship between LRG1 and the movement and advancement of ovarian cancer. From a mechanistic st