https://www.selleckchem.com/pr....oducts/gsk2643943a.h
istration Chinese Clinical Trail Registry. ChiCTR2000033848. III, retrospective observational study. Trial registration Chinese Clinical Trail Registry. ChiCTR2000033848.The small EDRK-rich factor 2 (SERF2) is a highly conserved protein that modifies amyloid fibre assembly in vitro and promotes protein misfolding. However, the role of SERF2 in regulating age-related proteotoxicity remains largely unexplored due to a lack of in vivo models. Here, we report the generation of Serf2 knockout mice using an ES cell targeting approach, wit