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15[1.42-2.99]; 2.90[2.13-4.01] and 1.29[1.10-1.69]; respectively). At admission, 103 patients (51.0 %) had a minor stroke (NIHSS less then 6). In these patients, plasma levels of C160, C220, and C240 ceramides were lower than that observed in patients with moderate-to-high clinical severity (P less then 0.001, all). In multivariate logistic regression analysis adjusted for other risk factors, higher levels of C160, C220, and C240 ceramides were associated with higher risk of moderate-to-high stroke (OR for one IQR increase 2.96 [2.05-4