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Weight management application developers and marketers should concentrate on the perceived value, safety, simplicity, and public awareness of health benefits. To attain an LDL-C level under 70 mg/dL in adults at a very high risk for atherosclerotic cardiovascular disease, the 2018 AHA/ACC cholesterol guideline recommends a maximally tolerated statin, combined with ezetimibe or PCSK9 inhibitors. We calculated the proportion of