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Elevated serum PFAS concentrations were also associated with reduced prevaccination measles antibody concentrations and increased morbidity. The present study documents that PFAS exposure has reached West Africa and that infants show PFAS-associated increases in morbidity and decreases in measles-specific antibody concentrations before and after vaccination. These findings support the evidence on PFAS immunotoxicity at comparatively low serum concentrations. https//doi.org/10.1289/EHP6517. The present study documents that PFAS exposure