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The subject also started glucocorticoid replacement therapy. Disorders in pubertal progression and gonadal function were noted. Dubowitz syndrome (DS) includes different clinical findings variably occurring. Subjects with a Dubowitz phenotype should be carefully monitored for endocrinological anomalies. The prompt recognition of potential life-threatening endocrinological condition for example adrenal insufficiency is mandatory in order to start an adequate and early treatment. Dubowitz syndrome (DS) includes different clinical findings v
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