https://nsc27223inhibitor.com/....hepatic-atrophy-reme
A reduction in -cell proliferation and glucose homeostasis was documented in Zhx2 (Zhx2BKO) mice in our experiments. We found that both Zhx2BKO-HFD and Zhx2BKO-db/db mice experienced glucose intolerance in the prediabetic and diabetic stages, with a decrease in beta-cell mass and impaired insulin secretion. A mechanistic investigation demonstrated that Zhx2's action was specifically directed towards the Pax6 promoter region, encomp