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7% with standard deviations less than 16.0%, and with relatively shorter analytical time. The established method was then used to screen imidazoles in 37 ambient PM2.5 samples. Ten targeted imidazoles were identified and quantified using imidazole standards, while five suspected imidazoles were identified without standards, and three imidazoles have not been reported before. Concentrations of the 10 targeted imidazoles ranged from 0.13 to 0.42 ng/m3. The established method enabled us to identify a wide range of imidazoles in ambient aeros