https://www.selleckchem.com/pr....oducts/ch6953755.htm
Classification of cancer should lead to informative patients' stratification and selective therapeutic vulnerabilities. A pathway-based classification of glioblastoma uncovered a mitochondrial subtype with a unique sensitivity to inhibitors of oxidative phosphorylation. Precision targeting of cancer metabolism could provide therapeutic opportunities to a lethal neoplasm and be translated to other tumour types.Genomic DNA is folded into loops and topologically associating domains (TADs), which serve important structural and regulatory