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Lenvatinib given in tandem with CQ demonstrated a more substantial decrease in VEGFA levels in the tumor supernatant compared to lenvatinib or CQ monotherapy. Suppression of autophagy led to a stronger cytotoxic and anti-angiogenic effect of lenvatinib, a finding corroborated by HUVEC migration, wound healing, and tube formation studies. Lenvatinib's cytotoxicity and anti-angiogenic properties were significantly boos
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