https://www.selleckchem.com/pr....oducts/ca-074-methyl
The selective activation of hypoxic signaling by metastatic breast cancer in the brain may have therapeutic implications.Cancer vaccines using synthetic long peptides (SLP) targeting tumor antigens have been tested in the clinic but the outcomes have been unimpressive, perhaps because these peptides elicit predominantly CD4+ T cell responses. We hypothesized that enhanced delivery of peptide antigens to, and uptake in, secondary lymphoid tissues should elicit more robust CD8+ and CD4+ T cell responses and improved anti-tumor
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