https://www.selleckchem.com/products/Y-27632.html
Severe acute pancreatitis (SAP) is associated with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS), but treatment of these conditions is difficult. We studied a rat model of SAP + IAH to determine the effect of oral administration of and butyrate (its major metabolite) on intestinal barrier functions. A total of 48 rats were assigned to four groups, with 12 rats per group Sham, SAP+IAH, SAP+IAH+ , and SAP + IAH + butyrate. SAP was induced by sodium taurocholate infusion into the biliopancreatic duct, intra-ab
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