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Therefore, in this article, we review Kynurenine and how it plays a vital role in BMSC dysfunction and bone loss with age. The morbidity of deep venous thrombosis (DVT) is increasing rapidly and the current therapeutic strategies for DVT are unsatisfactory. Accumulating evidence suggest that venous thrombi resolve (VTR) may provide new insights into DVT therapeutic strategies. The aim of this study was to investigate the role of curcumin in VTR process and try to reveal the potential mechanism. Immunofluorescence and HE staining were p