https://tie-2signaling.com/ind....ex.php/dna-rna-heter
The acute deterioration of mitochondrial function was associated with an increase in PRKN protein concentration, which in turn strengthened the pS65-Ub response. Our findings further corroborated the presence of elevated pS65-Ub immunopositive signals in mouse brains with syn overexpression and in the postmortem brains of human patients with the disease. Of particular interest, increased levels of pS65-Ub were associated with neuronal Lewy body-type synuclein pa
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