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Proximal MNBI was significantly lower in patients with both laryngopharyngeal and esophageal symptoms (17 cm above low esophageal sphincter [LES] L vs L + E vs E vs H = 3689.7 vs 2500.0 vs 3073.0 vs 3996.0; 15 cm above LES L vs L + E vs E vs H = 3155.9 vs 2553.4 vs 3198.9 vs 2985.2; P less then 0.001). Patients responded to proton pump inhibitor treatment also had lower proximal MNBI than those who did not (17 cm above LES 1834.0 vs 3500.0; 15 cm above LES 1946.5 vs 3432.6; P less then 0.001). CONCLUSION Decreased proximal MNBI can not
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