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78 and 0.93, respectively, p less then 0.01). Lactate pool size and the lactate-to-pyruvate ratio were not significantly correlated. © 2020 John Wiley Sons, Ltd.Intron-containing genes have the ability to generate multiple transcript isoforms by splicing, thereby greatly expanding eukaryotic transcriptome and proteome. In eukaryotic cells, precursor mRNA (pre-mRNA) splicing is performed by a mega-macromolecular complex defined as a spliceosome. Among its splicing components, U1 small nuclear ribonucleoprotein (U1 snRNP) is the sma
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