https://www.selleckchem.com/pr....oducts/upadacitinib.
BACKGROUND Triple progressive thermopreconditioning (3PTP) may induce high Hsp-70 expression to maintain cardiac function. We suggest that 3PTP may reduce myocardial ischemia/reperfusion (I/R) injury during organ transplantation through Bag3/Hsp-70 mediated defense mechanisms. METHODS Male Wistar rats were divided into sham control group and 72 hours after 3PTP in a 42°C water bath (3PTP) group. Rats underwent 60 minutes of ischemia by occlusion of the left anterior descending coronary artery followed by 240 minutes reperfusion. He
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