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Our model and materials are available to the community through crispr.pasteur.fr and Addgene. © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.There is growing interest in the role of gut microbiota in the pathophysiology of several diseases, including coronary artery diseases (CAD). Gut microorganisms may produce beneficial effects in myocardial ischemia either directly in the form of exogenous administration or indirectly by acting on fiber-rich food to produce important cardioprotective co
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