https://www.selleckchem.com/pr....oducts/Carboplatin.h
The analysis of the expression profile indicates that miR-21-5p was upregulated ( = 0.017), and miR-92a-3p was downregulated ( = 0.0005) in plasma-derived exosomes from HCC subjects, independently from the patient's characteristics. AUROC for HCC diagnosis based on AFP (alpha-fetoprotein) was 0.72. By integrating AFP and the relative expression of exosomal miR-21-5p and miR-92a-3p in a logistic regression equation for HCC diagnosis, the combined AUROC of the new exosomal miR HCC score was 0.85-significantly better than serum AFP alo
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