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We aimed to examine the effect of β2-agonists on anaerobic performance in healthy non-asthmatic subjects. Systematic review and meta-analysis. We searched four databases (PubMed, Embase, SPORTDiscus and Web of Science) for randomised controlled trials, published until December 2019, examining the effect of β2-agonists on maximal physical performance lasting 1 min or shorter. Data are presented as standardised difference in mean (SDM) with 95% confidence intervals (95% CI). 34 studies were included in the present meta-analysis. The studi