https://www.selleckchem.com/pr....oducts/a-438079-hcl.
The obtained estimates are close to the parameter values used in studies of electroporation.We measure the free energy of a model filament, which undergoes deformations and structural transitions, as a function of its extension, in silico. We perform Brownian Dynamics (BD) simulations of pulling experiments at various speeds, following a protocol close to experimental ones. The results from the fluctuation theorems are compared with the estimates from Monte Carlo (MC) simulation, where the rugged free energy landscape is produced b
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