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Pharmacological characterisation revealed that propofol enhanced GABAA -mediated currents and blunted GABA-mediated calcium entry more efficiently in female neurons than in males. Testosterone treatment did not erase such **** differences. These data suggest **** differences in the expression of GABAA receptor subtypes. CONCLUSION AND IMPLICATIONS GABA-mediated responses are ****ually dimorphic even in the absence of gonadal hormone influence, suggesting genetically biased differences. These results highlight the importance of GABAA recept
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