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Furthermore, the activation of the MAPK signalling pathway was identified as the potential mechanism through which KRT18 influenced GC processes. Keratin 18 plays a cancer-promoting role and might be a potential therapeutic target in the treatment of GC. Keratin 18 plays a cancer-promoting role and might be a potential therapeutic target in the treatment of GC. Diagnostic tests for fish allergy are hampered by the large number of under-investigated fish species. Four salmon allergens are well-characterized and registered with the WHO/IU