https://ndi-091143inhibitor.co....m/little-molecule-in
These findings underscore DUSP6's role as a negative regulator of Erk1/2 signaling, implying DUSP6 inhibition might be a novel therapeutic approach for neurodegenerative conditions subsequent to tGCI. The mechanism underlying steroid-dependent/frequently relapsing nephrotic syndrome (SDNS/FRNS) is, in part, rooted in immune dysregulation. While pediatric studies show a different picture, no major alterations to