https://www.selleckchem.com/
Available irisin antibodies still bind to patterns of unspecific serum proteins, which compromise reliable measurements of irisin with ELISAs. Absolute quantification of irisin with labeled peptides by mass spectrometry is an advanced method but requires a multi-step sample preparation introducing uncontrollable variations in the measurement. CONCLUSION Our data represent an explicit warning against measuring circulating irisin using available methods. Measuring irisin is akin to chasing shadows. OBJECTIVE Chronic inflammation of adipose tissues contributes
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