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The MCF-7 cell line's susceptibility to cytotoxicity was assessed in vitro via MTT and flow cytometry assays. The study's findings indicated that the Cur-loaded PAA-Starch-TiO2 formulation achieved enhanced effectiveness by improving drug bioavailability and controlled release mechanisms, contrasting with the free Cur. The nanocomposite's impact on cancer cell death, predominantly through apoptosis, was significantly more pronounced than the effect of free Cur, underscoring the efficacy


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