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The respective correlational coefficients were -0.83 (p 0.001) and -0.76 (p 0.001). The equations CPIRI(DM) = 670/(C/I)2.24 + 0.25 and CPIRI(HC) = 670/(C/I)2.24 - 1 (F = 1904.39, p 0.001) were obtained. Patients with insulin resistance exhibited severe coronary artery impairment and myocardial ischemia. In CAD patients there was no significant correlation between insulin resistance and the number of vessels involved. CPIRI can be used to effectively evaluate insulin resistance, and the combination of CPIRI and non-invasiv