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However, the mx2 positive rates in cohort B were higher in businessman (30.0% vs. 7.0%) and the tx4 positive rates in cohort B were higher in drivers (35.7% vs. 0.0%, P0.05). The optimal scale analysis showed that severe asthmatic patients who work indoor were more prone to be allergic to house dusts (Cronbach's alpha=76.4%). Patients with severe asthma in different occupations exhibited different sensitisation patterns. Avoid being contact with house dust and application of indoor air purifier should be considered for severe asthma


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