https://www.selleckchem.com/pr....oducts/hsp27-inhibit
The ability to inhibit host cell apoptosis is important for the intracellular ****tion of the obligate intracellular pathogen Coxiella burnetii, as it allows the completion of the lengthy bacterial ****tion cycle. Effector proteins injected into the host cell by the C. burnetii type IVB secretion system (T4BSS) are required for the inhibition of host cell apoptosis. AnkG is one of these anti-apoptotic effector proteins. The inhibitory effect of AnkG requires its nuclear localization, which depends on p32-dependent intra
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