https://www.selleckchem.com/
The source code is available at "https//github.com/yushanqiu/yushan.qiu-szu.edu.cn".We herein report the distal γ-C(sp 3 )-H olefination of ketone derivatives and free carboxylic acids. Fine tuning of our previously reported imino-acid directing group and use of the ligand combination of mono- N -protected amino acid (MPAA) ligands and electron-deficient 2-pyridone ligands were critical for the γ-C(sp 3 )-H olefination of ketone substrates. In addition, MPAA ligands were found to enable the γ-C(sp 3 )-H olefination of free carboxylic acids to form diverse 6