https://www.selleckchem.com/pr....oducts/brigimadlin.h
Amplification of 8q leads to a significant shift in the level of transcription of a large number of genes after exposure to chemotherapy. Both pediatric glioblastoma (pG and adult glioblastoma (aG are clinically devastating, and are known to have different molecular pathogenesis. Here, we focused on the role of ZEB2 in pGB and aGB. Following transfection with ZEB2 siRNA into pGB cells (KNS42) and aGB cells (U87 and U373), cell proliferation, migration and invasion, and cell cycle progression were evaluated. Targeted inhibition o
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