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rnate sample type (i.e., peripheral blood) or measurement methodology (i.e., blood gas) to guide treatment decisions. Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.Objectives Detecting instantaneous stroke volume change in response to altered cardiac preload is the physiologic foundation for determining preload responsiveness. Design Proof-of-concept physiology study. Setting Research simulation laboratory. Subjects Twelve healthy volunteers. Interventions A wirel


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