https://www.selleckchem.com/products/ABT-263.html
Finally, losartan treatment had limited efficacy in improving ocular phenotypes. In contrast with null or hypomorphic mutations, expression of a dominant-negative form of fibrillin-1 leads to disruption of microfibrils in the zonule of mice. This in turn causes lens dislocation and enlargement of the anterior chamber. Therefore, heterozygous mgΔ mice recapitulate the major ocular phenotypes of MFS and can be instrumental in understanding the development of the disease. In contrast with null or hypomorphic mutations, expression of a domi


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