https://www.selleckchem.com/pr....oducts/gw-441756.htm
In addition, it was found that the expression of p-extracellular signal-regulated kinase (ERK) and p-cAMP response element-binding protein (CRE increased in the TiO2 nanograin with the nanopore surface compared to the micro rough and nanotube surfaces relative to the osteogenic-related gene expression patterns. As a result, this study confirmed that the topographic structure of the surface is more affected by osteogenic differentiation than the pore size and that differentiation by specific surface composition components is by CREB.
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