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Analyses revealed a significant effect of vHC inhibition that was dependent on the type of threat exposure. Specifically, DREADD-induced silencing of vHC neurons reduced anxiety-like behavior in the EPM and LDT, without reliably affecting footshock-induced fear. These data add to a growing literature implicating the vHC as a key region involved in controlling the expression of anxiety in rodents, primates and humans.Astrocytes are activated after central nervous system (CNS) injury, such as spinal cord injury (SCI). Activated astrocytes
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