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herapy 2·7 [95% CI 1·3-5·6]; OR for RYGB vs medical therapy 0·7 [0·3-1·9]). Metabolic surgery is more effective than conventional medical therapy in the long-term control of type 2 diabetes. Clinicians and policy makers should ensure that metabolic surgery is appropriately considered in the management of patients with obesity and type 2 diabetes. Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Fondazione Policlinico Universitario Agostino Gemelli IRCCS. The Wee1 (WEE1hu) inhibitor adavosertib and gemcitabine have shown pre
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