https://www.selleckchem.com/products/tng-462.html
The knockdown of PVT1 attenuated the levels of inflammatory factors induced by PAF and destruction of cell-barrier function. The overexpression of PVT1 facilitated the pathological development. Additionally, miR-149 was identified as a target microRNA of PVT1, and the overexpression of miR-149 could reverse the effects of PVT1 on PAF-induced HSAECs. These findings suggest that PVT1 may represent a novel potential target for treatment of asthma. These findings suggest that PVT1 may represent a novel potential target for treatment of asth