https://sirtinolinhibitor.com/....unusual-amino-acids-
The consequence was a noticeable elevation of Cdk2, a p21 downstream target, hinting at an increased rate of G1/S phase transition within the hearts of Hdac1-deficient zebrafish. Cdk1, a further p21 and Cdc25 downstream target, was notably downregulated. The downregulation of Cdc25 protein expression was notably pronounced in Hdac1-deficient zebrafish embryos, contributing to reduced Cdk1 levels and suggesting a failure in proper G2/M
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