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Significantly higher levels of soluble interleukin-2 receptor (sIL-2R) and lactate dehydrogenase (LDH) were observed in DLBCL patients exhibiting B symptoms, reaching statistical significance (p = 0.0001 and p 0.0001, respectively). The peripheral blood microenvironment may play a role in the elevated sIL-2R and LDH levels seen in IVL, but additional studies are critical for verification. Glycogen resynthesis and subsequent same-day
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