https://osimertinibinhibitor.c....om/connection-betwee
The surfaces of protein-peptide interaction are usually limited in size and shallow, and there is a tendency for overlapping specificities in peptide-binding domain families. Thus, the process of identifying the elements crucial for selectivity can be quite complex. A diverse array of intracellular signaling and trafficking pathways utilize PDZ domains, a family of peptide-binding domains. Pathogens also directly target these domains, and a hallmark of
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