https://gsk3326595inhibitor.co....m/analysis-from-the-
Escherichia coli biofilms exhibit a heterogeneity in extracellular matrix production due to restricted curli gene expression in a segment of the bacterial population. Bimodal activation of the curli gene is demonstrated in homogenous, planktonic E. coli cultures, leading to a stochastic, binary split into curli-expressing and curli-lacking cell subpopulations during the transition to stationary growth conditions. Stochastic curli activation in individual E. coli cells, observed
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