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Obesity coupled with male **** frequently serve as key risk factors for sleep-disordered breathing (SD. Male diet-induced obesity (DIO) mice experienced a conjunction of respiratory impairment, characterized by hypoventilation, sleep apnea, and fragmented sleep episodes. Exploring the effects of DIO on breathing and sleep architecture in females has not been a priority in research. We conjectured that the negative impact of DIO on sleep and SDB is mitigated in female mice in comparison to ma