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In addition, the article investigates the difficulties inherent in 3D bioprinting and anticipates future directions in the field. The advancement of 3D bioprinting technology is set to bring new approaches to the in vitro printing of liver tissue, providing potent tools for drug development, testing, liver disease modeling, transplantation, and regeneration, which have profound academic and practical value. Although the field of drug design has seen considerable advancements, topological descripto