https://www.selleckchem.com/pr....oducts/muramyl-dipep
Thymineless death in Escherichia coli thyA mutants growing in the absence of thymidine (dT) is preceded by a substantial resistance phase, during which the culture titer remains static, as if the chromosome has to accumulate damage before ultimately failing. Significant chromosomal ****tion and fragmentation during the resistance phase could provide appropriate sources of this damage. Alternatively, the initial chromosomal ****tion in thymine (T)-starved cells could reflect a considerable endogenous dT source, making the