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24 (95% CI = 1.21-1.28, P less then .001). In subgroup analyses performed according to age and ****, all crude and adjusted hazard ratios of herpes zoster were higher in the peptic ulcer disease group than in the control group (each P less then .05). In another subgroup analysis according to follow-up periods, the crude and adjusted hazard ratios of herpes zoster were higher in the peptic ulcer disease group than in the control group except for less then 1 year periods after the index dates (each P less then .001).The hazard ratios