https://www.selleckchem.com/products/c-178.html
Gene-editing experiments commonly elicit the error-prone non-homologous end joining for DNA double-strand break (DS repair. Microhomology-mediated end joining (MMEJ) can generate more predictable outcomes for functional genomic and somatic therapeutic applications. We compared three DSB repair prediction algorithms - MENTHU, inDelphi, and Lindel - in identifying MMEJ-repaired, homogeneous genotypes (PreMAs) in an independent dataset of 5,885 distinct Cas9-mediated mouse embryonic stem cell DSB repair events. MENTHU correctly identified
כמו
תגובה
לַחֲלוֹק
