https://www.selleckchem.com/pr....oducts/stemRegenin-1
1E-07; age-at-onset top variant p value=9.3E-07). A polygenic risk score derived from publicly available Parkinson's disease summary statistics was a significant predictor of penetrance, but not of age-at-onset. This study suggests that variants within or near CORO1C may modify the penetrance of LRRK2 mutations. In addition, common Parkinson's disease associated variants collectively increase the penetrance of LRRK2 mutations. ANN NEUROL 2021;9082-94. This study suggests that variants within or near CORO1C may modify the penetranc