https://www.selleckchem.com/pr....oducts/oxidopamine-h
Rationale The stress response of heart rate (HR), which is determined by the plasticity of the sinus node (SAN), is essential for cardiac function and survival in mammals. As an RNA binding protein, cold-inducible RNA-binding protein (CIRP) can act as a stress regulator. Previously, we've documented that CIRP regulates cardiac electrophysiology at post-transcriptional level, suggesting its role in SAN plasticity, especially upon stress conditions. Objective Our aim was to clarify the role of CIRP in SAN plasticity and H
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