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Patients receiving anticholinergic combinations were younger (45.7 vs. 47.4 years, p less then 0.01) and had a longer inpatient stay (median 18 vs. 26.5 days, p less then 0.001). The prevalence of anticholinergic drug use in psychiatry is high. Further efforts need to focus on reducing the rate of anticholinergics and inappropriate medication especially in the elderly. Anticholinergic ADRs can be prevented by avoiding high-risk drug combinations. Replacing tricyclic antidepressants and first-generation antihistamines with drugs with